Noncatalytic function of PI3Kγ drives smooth muscle cell proliferation after arterial damage
نویسندگان
چکیده
منابع مشابه
Paclitaxel and Arterial Smooth Muscle Cell Proliferation
1. Bentham J, Rodriguez-Arnao J, Ross RJM. Acquired growth hormone resistance in patients with hypercatabolism. Harm Res. 1993;40:87-91. 2. Ross RJM, Chew SL. Acquired growth hormone resistance. Eur J Endocrinol. 1995;132:655-660. 3. Anker SD, Chua TP, Swan JW, Ponikowski P, Harrington D, Kox WJ, Poole-Wilson PA, Coats AJS. Hormonal changes and catabolic/anabolic imbalance in chronic heart fail...
متن کاملPaclitaxel and arterial smooth muscle cell proliferation.
1. Bentham J, Rodriguez-Arnao J, Ross RJM. Acquired growth hormone resistance in patients with hypercatabolism. Harm Res. 1993;40:87-91. 2. Ross RJM, Chew SL. Acquired growth hormone resistance. Eur J Endocrinol. 1995;132:655-660. 3. Anker SD, Chua TP, Swan JW, Ponikowski P, Harrington D, Kox WJ, Poole-Wilson PA, Coats AJS. Hormonal changes and catabolic/anabolic imbalance in chronic heart fail...
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The purpose of this study was to determine if hypoxia elicits different proliferative and apoptotic responses in systemic arterial smooth muscle cells incubated under conditions that do or do not result in cellular ATP depletion and whether these effects are relevant to vascular remodeling in vivo. Gene expression profiling was used to identify potential regulatory pathways. In human aortic smo...
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Elastases degrade the extracellular matrix, releasing growth factors and chemotactic peptides, inducing glycoproteins such as tenascin, and thereby promoting vascular cell proliferation and migration. Administration of serine elastase inhibitors reduces experimentally induced vascular disease. The ability to mount an intrinsic anti-elastase response may, therefore, protect against intimal/media...
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OBJECTIVES Methamphetamine use is a strong risk factor for stroke. This study was designed to evaluate arterial function and structure in methamphetamine users ultrasonographically. METHODS In a cross-sectional study, 20 methamphetamine users and 21 controls, aged between 20 and 40years, were enrolled. Common carotid artery intima-media thickness (CCA-IMT) marker of early atherogenesis, flow-...
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ژورنال
عنوان ژورنال: Journal of Cell Science
سال: 2020
ISSN: 1477-9137,0021-9533
DOI: 10.1242/jcs.245969